静脉滴注尼莫地平治疗脑出血的疗效研究

Study of cerebral hemorrhage treated with intravenous nimodipine

目的 观察尼莫地平治疗急性脑出血的临床效果。方法 应用前瞻性随机单盲方法 ,对 96例起病在 48h内经CT证实为急性脑出血患者 ,随机分为治疗组和对照组 ,比较治疗前后两组患者神经功能缺损程度积分差、颅内血肿体积及血肿周围水肿带面积的改变。结果 尼莫地平治疗组较对照组血肿周围水肿带面积明显缩小 (P <0 0 5 ) ,神经功能缺损评分明显改善 (P<0 0 1)。血肿体积则改变不明显。结论 在脑出血急性期应用尼莫地平治疗 。

AIM To observe the clinical curative effects of acute cerebral hemorrhage treated with nimodipine. METHOD Using method of foreseeable randomization of sampling, 96 cases of acute cerebral hemorrhage patients comfirmed by CT scan were divided into treatment group amd control subjects during 48 hours after the onset. Before ane after treatment, the integral difference of lesion degree of nerve function. Intracranial hematoma and the change of area of edema zome arceund hematome were compared between the two groups. RESULTS The area of edema zone arceund hematome of the treatment group shrunk obviously( P <0 05), the integral of lesion of nerve function chavged markedly ( P <0 01), Whereas the volrme of hematoma changed unobviously. CONCLUSION Acute cerebral hemorrhage is treated With nimodipine which can improue obviously the patients' condition.