带导药系统的快速扩张器的临床研究

Clinical study of a new expander with an agent delivery system and the effect of a chemical agent on tissue expansion

目的 探索快速组织扩张和提高皮瓣扩张质量的方法。方法 对 15例不同部位应用带导药 (罂粟碱 )系统的扩张器进行皮肤软组织扩张。结果 新型扩张法 (下简称NEM)和普通扩张法 (下简称GEM)扩张至额定容量所需要的平均时间分别为 2 6d和 5 1d ;全部扩张完成后两种扩张法扩张器的实际注水量超过额定容量的百分比分别为 92 41%和 2 7 12 %。扩张区皮肤血流量的比较(V) ,NEM :1 2 7± 0 2 8;GEM :0 6 4± 0 11。扩张表面积即时回缩率的比较 (% ) ,NEM :2 0 17± 1 74;GEM :38 2 6± 2 0 1。结论 采用此种方法 ,扩张速度快 ,皮瓣的即时回缩率低 。

Objective To search for a method to enhance tissue expansion. Method A new type of expander with an agent delivery system was used to expand soft tissue in 15 patients. During expansion Papaverine was delivered through the delivery system into the tissue around the expanders. Results It took 26 days to expand to the anticipated volume in the new expansion method group (NEM) and 51 days in the general expansion method group (GEM)(P<0.01). Before operation the NEM group was over expanded by 92.4% while the GEM group was over expanded by 27.12%. At full expansion the blood flow of the expanded area of the two groups was 1.27 (NEM)and 0.64 (GEM). The immediate skin retraction of the two groups was 20.17% (NEM)and 38.26% (GEM). Conclusion The new expansion method can accelerate expansion speed and improve the quality of expanded skin and flap.