颌骨软骨肉瘤(附8例病例分析)

Chondrosarcoma of the jaws,report of eight cases.

目的 :分析、探讨颌骨软骨肉瘤。方法 :复习我科近年来诊治的 8例颌骨软骨肉瘤的发病情况、病理类型、治疗方法、治疗结果和预后。结果 :颌骨软骨肉瘤下颌骨多于上颌骨 ,病理类型以高、中分化型 (一、二级 )多见。临床表现为无痛性肿块 ,可伴牙列的松动、张口受限、下唇麻木。治疗上应采取大块根治性外科切除术 ,无须行选择性颈清。复发与病理分级、术前化疗无关 (P >0 .0 5 ) ,主要取决于外科治疗的彻底性。结论 :颌骨软骨肉瘤是一种以局部侵袭为主的恶性肿瘤。

Objectives:To analyze and discuss chondrosarcoma of the jaws.Methods:We review the incidence,manifestation,pathologic classification,treatment methods,outcome and prognosis of 8 patients in our department during recent years.Results:In the original site of tumors,the majority is in the mandible.Grade 3 chondrosarcoma is not common.The salient syndrom of chondrosarcoma is painless mass,associating with loosening of teeth,trismus,numbness of the lower lip.In treatment methods,radical resection of the tumor is mandatory.There is no need of selective neck dissection.Recurrence of chondrosarcoma bear no relation to the preoperative chemothearpy and pathologic classification ( P >0.05),but is more dependent on radical resection of the mass tissue.Conclusions:Chondrosarcoma of the jaws is an aggressive malignant tumor.Long term follow up must be set up in these postoperative patients.