双门深经颅多普勒超声对脑动脉微栓子信号检测的敏感性和特异性研究

The sensitivity and specificity of detecting cerebral arterial microembolic signals by using bigated TCD

目的 :研究双门深经颅多普勒超声对微栓子信号 (MES)检测的敏感性和特异性。方法 :采用双门深TCD对 30例人工心瓣膜患者进行脑动脉微栓子检测 ,并与在线状态下有经验医师的人工判断 (作为黄金标准 )相比较。结果 :双门深TCD检测MES的敏感性为 6 0 2 % ,特异性为 6 7 8%。结论 :双门深TCD为识别、检测MES提供了新方法 ,但在线状态下的人工判断仍然是必要的。MES相对强度阈值对双门深TCD检测MES敏感性和特异性的影响值得进一步研究。

Objective:To study the sensitivity and specificity of detecting cerebral arterial microembolic signals (MES) using bigated TCD Method:In 30 patients with prosthetic cardiac valves,bigated TCD detection of MES was done and compared with on-line detection by an experienced investigator(used as the gold standard) Results:Bigated TCD presented sensitivity 60 2% and specificity 67 8% Conclusion:Bigated TCD adds a new dimension to the definition and detection of MES,but on-line detection of MES by an experienced investigator is inevitable The influence of MES relative intensity thresholds on sensitivity and specificity remains to be further studied \;