中国人肺癌生命质量表可行性的初步探讨

The possibility to establish the scale of quality of life (QOL) fit for Chinese lung cancer patients

目的 建立适合中国人的肺癌患者生命质量评价表 ,并对之进行可行性评价。方法 参照国外肺癌患者生命质量评价表 ,结合中国国情设计肺癌患者生命质量评价表 ,内容包含生物学、社会学、心理学三方面 ,分为 5个因子 6 5个条目。调查 35 5例经组织学或细胞学证实的肺癌患者 ,并将获得的评分与KPS评分比较。采用均数±标准差表示评分 ,t检验进行统计学分析。结果 所有患者、医师都能理解调查表的内容 ,仅有 2例患者 (均为初中以下文化程度 )在回答情感状况方面问题与经管医师有所不同。不同期别患者在总平均分、疾病症状、情感状况三方面有统计学差异 ;Ⅳ期患者的功能状况与Ⅰ～Ⅲ期患者亦有统计学差异 ;不同性别患者的情感状况相比也有统计学差异。结论 本表有良好的有效性、重复性和可行性。

Objective To establish and validate the scale of quality of life(QOL) fit for Chinese lung cancer patients. Methods By reviewing the other scales of QOL, we designed the new scale of QOL which include 5 factors with totally 65 items. It referred to biological and psychosocial aspects. Three hundred fifty five patients with lung cancer were reviewed. The scores were compared with KPS by different group mean t test. Results Patients and doctors could understand the contents of this scale, except for 2 patients who only accepted elementary education. Significant difference was observed in total score, gender and emotional well being among patients in different stage(P<0.05). The functional well being of stage Ⅳ patients was worse than that of other stage patients(P<0.05). The emotional well being of female patients was worse than that of male patients(P<0.05). Conclusion This scale is reliable, valid and capable in clinics.