植物转基因沉默研究进展

Advances of Researches on the Plant Transgene Silencing

随着转基因技术在植物中的广泛应用 ,转基因沉默受到越来越多的重视。转基因沉默可发生在转录和转录后两种水平 ,其基本特征就是依赖于同源的重复序列。转基因的重复拷贝间 ,转基因与同源的内源基因间及RNA病毒与同源转基因间都会发生基因沉默。可能有不同的机制导致转基因沉默 。

With the development of genetic engineering,more and more researchers pay attention to transgene silencing. Gene silencing takes place at transcriptional and post|transcriptional levels,and it is homology|dependent.Transgene silencing includes the inactivation of tandem repeats,trans|inactivation of allelic or ectopic copies,the coordinated silencing of a transgene and the endogenous homologous gene,and the cosuppression of RNA virus and the homologous transgene.There are different molecular mechanisms that induce gene silencing. Tansgene silencing is adapted as a procedure for virus|defence crop improvement and functional genomics in plants,this review introduces reseach progress on plant transgene silencing.