摘要
研究新疆维吾尔族人群 D16 S5 39、D13S317、D7S82 0和 D5 S818的 STR基因位点的基因及基因型分布 ,获得 4个基因座的群体遗传学数据 .采用 PCR扩增技术和基因扫描技术进行样本 STR遗传结构分析 ,并与其他种族、人群的等位基因频率进行比较 .结果表明 4个基因位点在新疆维吾尔族人群中均具有遗传多态性 ,4个基因座的基因型分布均符合 Hardy- Weinberg平衡定律 (P>0 .0 5 ) ,不同人群基因频率分布存在一定的差异 ,所得到的等位基因频率等数据可为遗传学研究。
The distribution of genes and genotypes of D16S539,D13S317,D7S820 and D5S818 were studied,and obtain genetics data in Xinjiang Uygur population. PCR technique and genescan technique were used to analyze the genetic structure of the 4 short tandem repeats(STR)loci. The allele frequencies were compared with other race or population data. The STR polymorphism at all of the 4 loci were observed in Xinjiang Uygur population. No deviation from Hard Weinberg equilibrium was observed. The allele distribution varies in different races and population. The data obtained can be used in population genetics investigation, individual identification and Paternity test.
出处
《生命科学研究》
CAS
CSCD
2001年第4期298-301,共4页
Life Science Research
基金
国家自然科学基金资助项目 ( 39970 40 1)
