医用生物蛋白胶用于腭裂整复术的疗效观察

Effect of fibrin glue in reparation of cleft palate

目的 观察医用生物蛋白胶应用于腭裂整复术的疗效。方法 随机将 68例患者分为两组 ,其中 38例使用生物胶填塞腭裂松弛切口患者为观察组 ,30例使用碘仿纱条填塞腭裂松弛切口患者为对照组。观察其术后体温、创口愈合、并发症等临床指标。结果 使用生物胶组术后体温恢复较快 ,术后 72h体温较手术当天低 0 .48℃ ,差异有显著性 ,P <0 .0 0 1;而使用碘仿纱条组术后 72h体温较手术当天差异无显著性 ,P >0 .0 5。使用生物胶组较使用碘仿纱条组创口愈合天数明显减少 ,经t检验有显著性差异 ,P <0 .0 1。术后并发症发生则无明显差异。结论 腭裂整复术应用医用生物蛋白胶可以减少患者术后反应 ,缩短创口愈合时间。

ObjectiveTo observe the effect of fibrin glue in reparation of cleft palate.Methods68 cases were divided into 2 groups: one with 38 using fibrin glue as experimental group and the other with 30 using iodoform gauze as control group. The temperature, henosis and complication were observed and compared.ResultsIn the experimental group, the temperature decreased by 0.48℃ in 72 h after operation compared with that in the operation. The difference was significant ( P <0.001). In the control group, the temperature changes remained insignificant between at the day receiving operation and in 72 h after operation ( P >0.05). The henosis period was obviously shorter in the experimental group than in the control group, t test showing the significance ( P <0.01). In view of complications, there existed no significance between the groups. ConclusionFibrin glue in reparation of cleft palate can decrease the temperature after operation and shorten the henosis time.