摘要
目的 :探讨中西医结合治疗狼疮性肾炎尿毒症的临床疗效。方法 :将 5 2例分为中西医结合组 2 8例 ,西医组 2 4例。西医组均先行腹膜透析 ,3天后开始采用激素标准疗程 ,并加用环磷酰胺冲击疗法 ;中西医结合组除西医治疗外 ,以“狼疮肾衰方”为主 ,辨证加减治疗。结果 :中西医结合组有效率为 92 .9% ,解脱透析持续时间为 ( 4 6.4±2 1.5 )月 ,解脱透析半年后血清肌酐为 ( 13 2 .4± 76.3 ) μmol/L ,副作用发生率为 14 .3 % ;西医组有效率为 75 .0 % ,解脱透析持续时间为 ( 3 8.4± 19.1)月 ,解脱透析半年后血清肌酐为 ( 2 0 8.3± 98.4 ) μmol/L ,副作用发生率为 3 3 .3 %。 结论 :中西医结合组在提高疗效、延长解脱透析持续时间、保持肾功能稳定、减少副作用方面 ,均显著优于西医组。
Objective: To study the efficacy of integrated traditional Chinese medicine and Western medicine (TCM-WM) on lupus nephritis with uremia. Methods: There were 28 in the TCL-WM group and 24 cases in WM(Western medicine alone) group. Results: In TCM-WM group, the effective rate and duration of withdrawing from dialysis were 92.9% and 46.6±21.5 months respectively, while in WM group they were 75.0% and 38.4±19.1 months respectively. Half year after the withdrawal from dialysis, serum creatinine (Scr) was 132.4±76.3 umol/L in TCM-WM group and 208.3±98.4 umol/L in WM group. Incidence of side effects was 14.3% in TCL-WM group and 33.3% in WM group. Conclusion: TCM-WM significantly improves the effective rate, prolong the dialysis-free duration after withdrawn from dialysis, stabilize renal function and reduce incidence of side effects.
出处
《中国中西医结合肾病杂志》
2001年第9期518-519,522,共3页
Chinese Journal of Integrated Traditional and Western Nephrology
