摘要
目的 分析双表型急性白血病的免疫表型、临床疗效和预后情况。方法 采用流式细胞仪分析急性白血病的免疫表型 ,双表型急性白血病诊断依据EGIL标准。结果 双表型急性白血病构成比为 6 2 % ,其中B系、髓系抗原共同表达的占6 6 7% ,T系、髓系共同表达的占 33 3 %。CD34阳性率为 44 4% ;9例患者中治疗完全缓解 3例 ,部分缓解 1例 (11 1% ) ,总有效率 44 4%。结论 免疫表型对双表型急性白血病诊断及预后有重要意义 ,以B系和髓系共同表达最常见 ,缓解率低 ,易复发 ;P170 与BAL预后有关。
AIM To analyze the immunophenotypes and the treatment outcome of adult biphenotypic acute leukemia (BAL). METHODS Immunophenotypes were all examined by using flow cytometry. BAL was diagnosed according to EGIL Scoring system. RESULTS The incidence of BAL in acute leukemia was 6 2 Percentage for coexpression of B lymphoid and myeloid antigens was 66 7%, for lymphoid and myeloid antigens was 33 3%; CD 34 was expressioned in 44 4% of the BAL ones; 6 of 9 patients achieved completed remission (CR), 3 of 9 patients not. CONCLUSION Immunotypes were important for the diagnosis and prognosis of BAL; P170 has relation to the prognosis of BAL.
出处
《安徽医药》
CAS
2001年第2期112-114,共3页
Anhui Medical and Pharmaceutical Journal
关键词
白血病
双表型
流式细胞仪
免疫表型
BAL
coexpression of B/M antigens
leukemia
biphenotypic
immunophenotype
flow cytometry
