摘要
目的 :探讨舒必利预防 /控制顺铂化疗后所致消化道迟发性恶心、呕吐的效果及有关护理措施。方法 :采用自身对照法 ,观察 86例恶性肿瘤患者对以顺铂为主的联合化疗后于第 1周期口服舒必利 ,第 2周期肌肉注射胃复安 ,预防迟发性恶心、呕吐疗效的对比观察。结果 :第 2、3、4天有效率舒必利为 83.7%、83.7%、93% ,胃复安为 5 0 %、5 3.7%、81.4% (P<0 .0 5 )。结论 :舒必利疗效优于胃复安 。
Objective:To investigate the effect of Sulpiride on preventing and controlling nausea and vomiting after the chemical therapy with cisplatin.Methods:86 cases of cancer,mainling treated with cisplatin were investigated.The patients were given Sulpiride orally in the first week and Metoclopramide injection in the second week.The effects of Sulpiride and Meloclopramide on preventing nausea and vomiting were compared.Results:The effective rate of Sulpiride and Metoclopramide in 2,3,4 days were 83.7%(50%),83.7%(53.7%) and 93%(81.4%),respectively ( P <0.05).The reaction of extrapyramidal system was 2.3% in the patients of sulpiride group and 9.3% in the patients of metoclopramide group ( P <0.05).Conclusion:The effect of Sulpiride is better than that of Metochopramide and its side-effect is also light.
出处
《华夏医学》
2001年第5期577-578,共2页
Acta Medicinae Sinica
关键词
顺铂
恶心
呕吐
舒必利
护理
化疗
cisplatin
nausea
vomiting
prevention
sulpirid
nursing
