RMIⅡ在术前鉴别卵巢肿瘤性质中的价值

The value of the risk of malignancy index Ⅱ in preoperative diagnosis of ovarian cancer

目的 探讨恶性肿瘤风险指数Ⅱ (RMIⅡ )对卵巢肿瘤术前良、恶性预测的临床价值。方法 本组收集年龄 >3 0岁的卵巢肿瘤患者 186例 ( 1999年 1月至 2 0 0 0年 12月 ) ,其中良性肿瘤 112例 ,恶性肿瘤 74例。分别根据术前血清CA12 5水平、超声分数、绝经状态以及RMIⅡ ,对上述肿瘤的良、恶性进行模拟预测 ,比较其敏感性、特异性及阳性预测率。结果 RMIⅡ对卵巢肿瘤良、恶性预测以RMIⅡ值 2 0 0为界的敏感性为89.2 % ,特异性为 85 .7% ,阳性预测率为 80 .5 % ,阴性预测率为 92 .3 %。分别较其它三项预测指标的敏感性、特异性、阳性预测率、阴性预测率为高。结论 RMIⅡ较其它指标对卵巢肿瘤良、恶性的预测更为准确 。

Objective To evaluate the ability of the risk of malignancy index II (RMI II) to discriminate the benign ovarian neoplasms from the malignant ones. Method 186 cases with ovarian tumors, whose age were more than 30 years old, were collected from Jan. 1999 to Dec. 2000. 112 cases were benign tumors and 74 cases were malignant ones .The sensitivity, specificity and positive predictive value in discriminating the benign tumors from the malignant ones were compared by the serum CA125 level, ultrasound findings, menopausal status and the RMI II.Result The sensitivity, specificity, positive and negative predictive value of the RMI II, whose cut-off level of 200 was to indicate malignant tumors, were respective 89.2%, 85.7%, 80.5% and 92.3% and were more accurate than the other three individual criterions in diagnosing tumors.Conclusion The RMI II is able to discriminate more accurately malignant tumors from benign ones than the other individual criterions and it is a simple method that can be introduced easily into clinical practice.