A型肉毒毒素对痉挛型脑瘫的解痉效果及功能预后影响

Effects on reducing spasm and functional outcome in botulinum toxin A for treatment of spastic cerebral palsy

目的 :探讨A型肉毒毒素 (BTA)对痉挛型脑性瘫痪的临床治疗价值。方法 :选择 2 3例脑瘫儿童采用BTA神经阻滞治疗肌痉挛 ,上肢肌群注射BTA的起始剂量为 1- 2U/kg ,下肢肌群的BTA注射的起始剂量为 3-U/kg。结合康复治疗和下肢支具。结果 :经BTA注射后的肌张力有明显降低 ,关节活动度有一定程度的提高 ,改善了患者的运动功能。结论 :BTA对脑瘫儿童肢体痉挛肌群进行神经阻滞注射 ,有缓解肌痉挛。

Objective: To observe the clinical value of botulinum toxin A(BTA) on the treatment of spastic cerebral palsy. Method: Thirteen children were injected with BTA for spasticity treatment, the beginning dosage was 1-2U/kg on upper extremities muscles and 3-5U/kg on lower extremities muscles. Result: Injection of BTA help to decrease the muscle tone, improve the ROM and patient′s motor function. Conclusion: The clinical effect of BTA is reliable on cerebral palsy by the injection of BTA with reducing spasm and improving function.