聚吖啶橙修饰电极的电化学行为及其对肾上腺素的电催化性能

Electrochemical Behavior of Poly(acridine orange) Modified Electrode and Its Electrocatalytic Performance for Epinephrine

研究了聚吖啶橙 (POAO)修饰电极及其电化学性能 ,并用于肾上腺素 (EP)的电化学测定。EP在POAO修饰电极上产生一灵敏的氧化峰 ,与裸玻碳电极 (GCE)相比 ,其峰电位负移了 2 30mV ,明显降低了EP的氧化过电位。在pH 6 .0的磷酸氢二钠 柠檬酸缓冲溶液中 ,氧化峰电流与EP的浓度在 4 .5× 10 - 7～ 9.2× 10 - 5mol L范围内呈良好的线性关系 ,检出限为 1.0× 10 - 9mol L。

Poly(acridine orange) (POAO) modified electrode has been fabricated and was applied to the electrochemical measurement of epinephrine ( EP). A sensitive oxidation peak of EP was observed at POAO electrode. The oxidation overpotential was reduced by 230 mV compared with the bare glassy carbon electrode. In pH 6.0 phosphate-citric acid buffer solution, the oxidation peak current was linear depending on the EP concentration between 4.5 x 10(-7) and 9.2 x 10(-5) mol/L. The detection limit is 1.0 x 10(-9) mol/L. It has been applied to the determination of EP in injection and human serum.