儿童眼部肿瘤341例临床分析

Analysis of341Cases of Ocultar Tumors in Children

目的 :分析儿童眼部肿瘤的发病特点。方法 :对341例儿童眼部肿瘤患者的年龄、性别、肿瘤发生部位及病理类型进行回顾性分析。结果 :患儿平均发病年龄4.2岁 ,341例儿童眼部肿瘤中 ,良性肿瘤12种233例(68.33 %) ,恶性肿瘤3种108例(31.67 %)。结论 :视网膜母细胞瘤105例(97.33 %) ,在恶性肿瘤中发病率最高。从发现症状到就医的早迟 ,视网膜母细胞瘤不同时期的平均发生时间有显著性差异(P<0.05)。定期对5岁以内儿童进行眼部检查 。

Objective:To analyze the prevalence and pathological types of ocular tumors in children patients.Methods:The histry,age,sex,locations of ocular tumors and their pathological types of341children patients were retrospectively reviewed and analyzed.Results:The mean age of341caseswas4.2years(range:3months to14years).Among341children patients,233ocular tumors(68.33%)were pathologically proven benign tumors belonged under12types of benign tumors,and108ocuˉlar tumors were pathologically proven malignant tumors belonged under3types of malignant tumors.Conclusions:The most prevalent type of malignant ocular tumor in108children patients was retinblastoma(105/108,97.22%).The length of the time period from the occurrence of the first symptom or sign to the patient presented himself for an ophtholmologic examinatior at the hospital was an independent prognostic factor with significance(P<0.05).Therefore,the early discovery,the early diagnosis and the early threatment are closely related to higher survival rate of retinoblastoma patients.We suggest that regular ophthalmoˉlogic checkup for children under the age of5years old should be emphasized.