摘要
腈的酶法水解不仅反应条件温和 ,而且高效性、高选择性 ,在光学活性羧酸及其衍生物的合成中具有巨大的应用潜力。综述了催化腈水解的酶类、反应类型、反应特性、影响反应的因素及其在工业上的应用前景。
Enzymatic hydrolysis of nitrile was performed under mild conditions and afford high efficiency and selectivity,thus being highly potential for the synthesis of optically active carboxylic acids and their derivatives.The type of nitrile-hydrolyzing enzymes and hydrolysis reactions,reaction characteristics,factors influencing the hydrolysis and the prospect for its application to industrial production were reviewed in this paper.
出处
《微生物学通报》
CAS
CSCD
北大核心
2001年第6期76-81,共6页
Microbiology China
基金
国家自然科学基金资助项目 (No .2 0 0 76 0 1 9)~~