摘要
目的 探讨柴胡注射液与硫酸庆大霉素注射液配伍的疗效、毒副作用以及稳定性等方面的变化 ,以验证两药配伍应用的可行性。方法 采用理化分析、药理试验、薄层析检查、微生物测定、临床验证观察等方法进行系统研究。结果 两药配伍后稳定性好 ,解热作用增强 ,对效价无影响 ,无明显毒副作用和不良反应。结论 柴胡注射液与硫酸庆大霉素注射液配伍后 ,质量稳定、疗效可靠、使用安全。
Objective To explore the therapeutic effectiveness,the toxic and side effects and the change of stability in the compatible application of injectios of bupleurum and gentamycin sulfate so as to verify the applicable possibility of these two injectios.Methods Physicochemical analysis,pharmacological test,thin-layer examination,microbiological assay and observation of clinical verification were used to carry out systematic study.Results The stability of the compatibility of both injections works well,the antipyretic effect has been strengthened with no dovious influence on potency,with no evident toxic and side effects and with no bad reaction.Conclusion The compatibility of these two injections has stable quality with reliable therapeutic effectiveness and safe application.
出处
《临沂医学专科学校学报》
2001年第3期193-196,共4页
Journal of Linyi Medical College
基金
临沂市卫生科技发展计划项目
编号 :L92K0 5。
关键词
柴胡注射液
硫酸庆大霉素注射液
理化试验
药理试验
效价测定
临床观察
药物配伍
Bupleurum injection
Gentamycin sulfate injection
Physicochemical test
Pharmacological test
Potency determination
Clinical observation
