摘要
对15例骨髓增生异常综合征(MDS)病人的免疫状态进行规察。结果表明,MDS病人周围血淋巴细胞转化率,E-玫瑰花环形成试验,D细胞百分比和T细胞百分比均明显低于正常人;血清免疫球蛋白IgA,IgD,IgM含量亦较正常人明显降低。提示免疫状态的监测对阐明MDS的发病机理及转化起重要作用。
The immune state of 15 cases of myelodysplastic syndrome were observed.
The rate of lymphocytic change, rate of erythrocyte rosette formation, and the
lymphocytic subsets were measured. The results showed that the decrease and
inadequacy of T-lymphocytes, which are important in cellular immunity, caused
the failure of the regulative function of the myeloblast and the immunosurveillance
of the myeloblast. The measurement of the content of immunoglobin, circulating
immune complexes and the complements showed that the decrease in the content
of immunoglobin was an important cause of death through infection in cases of
myelodysplastic syndrome. The immune state and immunosurveillance are consid-
ered important in explaining the cause and the transformation of myelodysplastic
syndrome.
出处
《青岛医学院学报》
1991年第2期147-149,共3页
Acta Academiae Medicinae Qingdao Universitatis
关键词
MDS
骨髓增生
细胞免疫
myelodysplastic syndrome
seroimmunity
cellular immunity
