电荷转移络合分光光度法测定吡拉西坦片含量

Determination of piracetam tablets by charge transfer complex spectrophotometry

目的：建立用电荷转移络合分光光度法测定吡拉西坦片含量的方法。方法：利用碘与吡拉西坦在二氯乙烷中形成荷移络合物，在227.2 nm波长处测定吡拉西坦片的 含量。结果：平均回收率为99.57%，RSD为1.24%，在4～220 μg·ml-1浓度范围内线性良 好，r=0.9998。结论：电荷转移络合分光光度法可简便、快速、准确地检测片剂中吡拉西坦的含量。

OBJECTIVE To establish an accurate method to determine piracetam in tablet by c harge transfer complex spectrophotometry method. METHODS Piracetam reacted with iodine in dichloroethane forming a charge transfer comp lex,it can be quantitatively determined by spectrophotometric methode at 227.2 nm. RESULTS The arerage recovery was 99.6% and RSD=1.2%.The linear range was 4～22 0 μg·ml-1, r =0.9998. CONCLUSIONS The method can be used to determine the concentration of piracetam in tablet s imply,rapidly and accurately.