摘要
目的:建立用电荷转移络合分光光度法测定吡拉西坦片含量的方法。方法:利用碘与吡拉西坦在二氯乙烷中形成荷移络合物,在227.2 nm波长处测定吡拉西坦片的 含量。结果:平均回收率为99.57%,RSD为1.24%,在4~220 μg·ml-1浓度范围内线性良 好,r=0.9998。结论:电荷转移络合分光光度法可简便、快速、准确地检测片剂中吡拉西坦的含量。
OBJECTIVE To establish an accurate method to determine piracetam in tablet by c harge transfer complex spectrophotometry method. METHODS Piracetam reacted with iodine in dichloroethane forming a charge transfer comp lex,it can be quantitatively determined by spectrophotometric methode at 227.2 nm. RESULTS The arerage recovery was 99.6% and RSD=1.2%.The linear range was 4~22 0 μg·ml-1, r =0.9998. CONCLUSIONS The method can be used to determine the concentration of piracetam in tablet s imply,rapidly and accurately.
出处
《中国医院药学杂志》
CAS
CSCD
北大核心
2001年第10期607-609,共3页
Chinese Journal of Hospital Pharmacy