美扑伪麻薄膜衣片与素片的稳定性对比研究

The Cmpared Research of the Stability ot Film-coaxing Tablets and Conrentional Tablets of Compound Hydrobromide Dextromethorphan Tablets

美扑伪麻薄膜衣片与素片在温度40±2℃、相对湿度为75±5%的条件下放置6个月,通过美扑伪麻薄膜衣片与素片的稳定性对照试验,考察薄膜包衣技术能否提高该制剂的稳定性及对药物溶出的影响。结果表明美扑伪麻薄膜衣片较美扑伪麻素片对潮湿稳定,溶出度也未发生明显变化。

The film-coating tablets and conrentional tablets of Compound Hydrobromide Dextromethorphan Tablets,wereput aside in six months under the condition of 40±2℃ and RH75±5%.By means of the compared experiments of the stability of,the two draugs It was examined whether the film- coating technology can improve the stability of the pharmaceutical preparations and influence their dissolation. The results obtained indicate that the film-coating tablets of Compound Hydrobromide Dextromethorphan Tablets,showed a higher stability than the conventional tablets of Compound Hydrobromide Dextromethorphan Tablets,on moisture.And no abvious difference between their on the dray's dissolation were observed.