心室复极空间不一致性表示方法的探讨

AN EFFECTIVE METHODS TO DEFINE THE SPATIAL DISPERSION USED IN REPRESENTING THE HETEROGENEITY IN VENTRICULAR REPOLARIZATION

本文采用二次样条小波变换提取心电信号的特征点 ,从羊心脏表面 6 4通道的心电信号中 ,提取各通道的QT间隔和兴奋恢复间隔 (ARI) ,分别求出二者以极差法、标准差法和变异系数定义的离散度 ,通过统计检验P值 ,比较三种方法定义的QT和ARI离散度在心肌缺血前后的变化 .发现三种定义的QT离散度 ,在心肌缺血前后都不具有显著性差异 ,并以变异系数离散度的P值最大 .而心肌缺血使得ARI离散度明显增加 ,三种定义的ART离散度在心肌缺血前后都具有显著性差异 ,以变异系数离散度的P为最小 ,可见三种方法定义的离散度均有效 ,而变异系数离散度较极差法。

An effective method to define the spatial dispersion used to represent the ischemia induced heterogeneity in ventricular repolarization is investigated. The algorithm based on wavelet transformation is adopted to analyze QT and ARI from a 64-channel epicardial ECG data of an ischemic sheep. The quadratic spline wavelet is used to extract QRS with 2 1 scale and T wave with 2 5 scale, and then Q, T, A and R points are determined by definition. The epicardial QT and ARI dispersions are calculated with three methods: extremum difference (ED), standard deviation (SD) and coefficient of variation (CV). It is found that there is no significant difference in QT dispersion before and during ischemia regardless of the dispersion method with CV method having the largest P value. Meanwhile ARI dispersion on the epicardium is significantly increased during ischemia with P CV being the minimum. Furthermore, although the three methods are effective in representing the spatial dispersion, the CV method has a statistical advantage.