无症状脑梗死患者血浆中内皮素、一氧化氮含量的研究

Study of Endothelin and Nitric Oxide in Plasma of Asymptomatic Cerebral Infarct

目的 探讨无症状脑梗死患者的血浆内皮素 (ET)、一氧化氮 (NO)变化与脑梗死的关系。方法 检测 37例无症状脑梗死患者血浆ET ,NO含量。结果 无症状脑梗死患者ET水平明显高于正常对照组 (P <0 .0 5 ) ,而NO水平明显低于正常对照组 (P <0 .0 5 )。结论 无症状脑梗死患者ET ,NO水平可作为临床诊断的一种参考指标 ,并提示无症状脑梗死患者宜早期进行抗脑缺血的治疗。

Objective To study the change of endothelin(ET)and Nitric oxide(NO)in asymptomatic Cerebral infarct(ACI). Method The levels of ET and NO in plasma of ACI group and the controls group were observed. Result Plasma ET in ACI had significantly increased( P <0.05 vs the controls group). but plasma NO in ACI had significantly decreased( P <0.05, vs the controls group). Conclusion Plasma ET and NO had important reference value in estimating early diagnosis and guiding therapy effectively in ACI.