不同年龄组术后硬膜外自控镇痛效果评估

Curative Effect of Postoperative Extradural AutocontrolAnalgesic in Different Age Patients

目的 观察比较三组不同年龄的病人术后硬膜外自控镇痛 (PCEA)镇痛效果。方法 88例ASAⅠ～Ⅱ级手术病人 ,按年龄分为三组 ,组Ⅰ :<45岁 ;组Ⅱ :45～ 6 5岁 ,组Ⅲ :>6 5岁 ,所用药物均为芬太尼、布比卡因与氟哌啶的混合液 ,按一定模式给药 ,观察记录镇痛效果。结果 组Ⅰ、组Ⅱ病人用药量无显著差异 (P >0 .0 5 ) ,组Ⅲ较组Ⅰ、组Ⅱ用药量明显减少 (P <0 .0 1) ,三组间的VAS评分无显著差异 ,镇痛效果明显。结论 老年人采用术后PCEA方法在给药模式上 ,须根据病人的年龄及生理改变酌情减量。

Objective To compare the curative effect of postoperative Extradural Autocontrol Analgesic (PCEA) in three different ages groups. Methods 88 ASA Ⅰ-Ⅱ grade operation patients were divided into three groups by ages: Ⅰ group<45 years old, Ⅱ group 45-65 years old, Ⅲ group>65 years old. Used medicine was the mix of fentanyl, bupivacaine and holoperidol, and the medicine was used with definite mode. The analgesic effect was recorded. Results There was no obvious difference with used drug dose between Ⅰ group and Ⅱ group ( P >0.05). In Ⅲ group the used drug dose was obviously less than Ⅰ group and Ⅱ group ( P <0.01). In three groups, VAS grade had no obvious difference. The analgesic effect is obvious. Conclusion For senile patients, the used drug dose should be extenuatingly decreased according to their ages and physiological status when PCEA method was adopted.