中晚期卵巢癌盆腔介入治疗的临床分析

Clinical Significance of the Iliac Artery Interventional Chemotherapy and Embolization in Cases with Meta-late Phase Ovarian Carcinomas

目的 探讨中晚期卵巢癌盆腔动脉介入化疗栓塞的疗效及临床意义。方法 2 2例中晚期卵巢癌 ,其中Ⅱ期 10例 ,Ⅲ期 8例 ,Ⅳ期 4例。术前盆腔动脉化疗栓塞 6次 ,术后 36次。观察评定远期疗效 (1个月～ 2年 )。结果 有效率70 % ,其中 2例Ⅳ期卵巢癌伴肝转移患者 ,经介入化疗 2～ 3次后 ,肿瘤明显缩小 ,行卵巢癌减灭术 ,术后病理淋巴结无转移。B超示肝转移灶缩小 ,术后继续行盆腔介入化疗 ,存活至今未复发。结论 盆腔动脉介入化疗是治疗中晚期卵巢癌的安全有效的方法。术前介入化疗能使肿瘤等原发灶明显缩小。提高手术切除率。术后介入化疗 ,能有效控制肿瘤复发延长病人存活期。

Objective To analysis the clinical significance of the iliac artery interventional chemotherapy and embolization in meta-late phase ovarian carcinomas. Methods Among 22 cases with meta-late phase ovarian carcinoma, there were 10 cases of stage Ⅱ, 8 of stage Ⅲ, and 4 of stage Ⅳ. The total number of treated times 42, including 6 times at preoperative and 36 times at postoperative. The effects were observed and followed up during the period of afterward. Results The effective rate was 70%. 2 cases of the stage Ⅳ(2/4)who also had the hepatic metastasis appeared marked decrease of their tumor size. And the radical operations were operated on them successful. They were still alive. Conclusion The interventional chemotherapy is a safe and operative treatment in patients with meta-late phase ovarian carcinomas. It could decrease the size of the tumors significantly and thus could elevates the possibility of tumors resection. Keeping regular interventional chemotherapy during postop rative period might prolong their survival period.