蕲蛇酶治疗急性脑梗死的临床研究

The clinical study of therapy to the acute cerebral infarction with Qi snake enzyme

目的评价蕲蛇酶治疗急性脑梗死的疗效及安全性。方法将240例急性脑梗死患者随机分为静脉溶栓组及对照组 ,观察溶栓组及对照组治疗效果及头颅CT梗死灶变化 ,并观察蕲蛇酶应用时间早晚对治疗效果及头颅CT梗死灶的影响。结果溶栓组显效率和有效率明显高于对照组 ,早期应用者显著高于晚期应用者 ;溶栓组头颅CT梗死像缩小或消失百分率明显高于对照组。结论蕲蛇酶治疗急性脑梗死能显著改善临床症状及头颅CT梗死像 ,降低致残率 。

Objective To estimate the curative effect and security of therapy to the acute cerebral infarction with Qi snake enzyme. Methods 240 cases of acute cerebral infarction were divided into the group dissolving thrombus in vein or the control group randomly. To observe the curative effect and the change of cerebral CT infarction area in two groups and the effects of what time the Qi snake enzyme was used on the curative effect and the cerebral CT infarction area. Results The distinct efficiency rate and efficiency rate in the group dissolving thrombus were higher than that in the control group significantly, and the efficiency rate in the case using the enzyme early were higher than that in the case using enzyme later; the percentage of lessening or disappearing of cerebral CT infarction image were higher than that in the control group significantly. Conclusion Using QI snake enzyme to treat the acute cerebral infarction can improve clinical symptom significantly and cerebral CT infarction image and reduce disabled rate with high security.