摘要
P73 基因是Kaghad等在 1997年克隆得到的一个新基因 ,与P53 具有相似的结构、功能与活性 ,但其是否作为一个抑癌基因发挥作用 ,目前尚存在争论。本文就P73 的发现定位、结构、功能及其与肿瘤发生发展的关系作一综述。
Gene P 73 was found by Mourad Kaghad in 1997, which shares considerable homology with the tumor suppressor P 53.However, it is unclear whether this protein can operate in a network of development and cell cycle controls as a tumor suppressor. In this article, we shall discuss the cloning, location, expression and functions of this new candidate tumor suppressor gene.
出处
《山西中医学院学报》
2001年第2期27-28,共2页
Journal of Shanxi College of Traditional Chinese Medicine