区域灌注疗法治疗原发性肝癌的临床观察

Clinical observation of regional infusion chemotherapy in primary liver carcinoma

目的 探讨肝动脉、门静脉双重插管区域灌注化疗在中晚期不能切除原发性肝癌应用方法及临床疗效。方法 将1988年～1999年68例中晚期不能切除原发性肝癌行肝动脉、门静脉插管皮下埋藏灌注器区域灌注化疗,对其疗效进行观察。结果 本组显效率22.1％、有效率57.3％、无效率20.6％。半年带瘤存活率73.5％、一年带瘤存活率55.9％、二年带瘤存活率8.8％。结论 中晚期不能切除的原发性肝癌使用肝动脉、门静脉双重插管灌注化疗,可以改善临床症状、延长存活期。

Objective To explore the curative effect of double intubated hepatic artery and portal vein regional infusion chemotherapy in non-resectable metaphase or late primary liver carcinoma. Methods The curative effect of 68 patients with non-resectable metaphase or late primary liver carcinoma embedded with drag delively system to hepatic artery and portal vein for regional infusion chemotherapy 1988 to 1999 were observed. Results The significant effective rate was 22.1%, effective rate 57.3% , ineffective rate 20.6% . The survival rate of half a year was 73.5% , survival rate of a year 55.9% and survival rate of two years 8.8% . Conclusion Double intubated hepatic artery and portal vein regional infusion chemotherapy in non-resectable metaphase or late primary liver carcinoma may ameliorate symptoms and prolong survival time.