云南土壤真菌07-11号菌株中的活性成分

Active Constituents of the Soil Fungus 07-11 Collected from Yunnan

从云南土壤真菌 0 7 11发酵液乙酸乙酯层浸膏中得到 5个活性成分 ,经光谱数据分析和理化鉴别 ,分别鉴定为邻羟基苯甲酸 (Ⅰ )、4 ,6 二羟基 5 甲基 1(3H)异苯骈呋喃酮 (Ⅱ )、2 甲酰基 3,5 二羟基 4 甲基苯甲酸 (Ⅲ )、N (4 羟基 2 甲氧苯基 )乙酰胺 (Ⅳ )以及麦角甾 7,2 2 二烯 3,6 二酮(Ⅴ ) ,它们对稻瘟霉分生孢子及菌丝体都有一定抑制作用。其中化合物Ⅳ为首次分离得到的天然产物 。

Five active compounds have been isolated from the ethyl acetate extract of the fermentation of fungus 07 11 obtained from the soil of Yunnan Province.They were identified as 2 hydroxybenzoic acid(Ⅰ),4,6 dihydroxy 5 methyl 1(3 H ) isobenzofuranone(Ⅱ),2 formyl 3,5 dihydroxy 4 methyl benzoic acid(Ⅲ), N (4 hydroxy 2 methoxyphenyl)acetamide(Ⅳ) and ergosta 7,22 diene 3,6 dione(Ⅴ) respectively on the basis of spectral data and physical and chemical identification.They all could induce morphological deformation of mycelia geminated from conidia of Pyricularia oryzae .Compound Ⅳ was first isolated from nature and its spectral data were reported for the first time.