一氧化氮合酶抑制剂与脑缺血
摘要
在脑缺血过程中,一氧化氮(NO)的产生显著增加,对脑缺血既有保护作用又有加重损害的作用.在NO形成过程中由于一氧化氮合酶(NOS)不同,因而不同NOS抑制剂对脑缺血的作用也不尽相同,这与NOS抑制剂的类型。
出处
《国外医学(脑血管疾病分册)》
2001年第6期365-367,共3页
Foreign Medical Sciences Cerebrovascular Diseases
参考文献18
-
1Tokime T, Nozaki K, Sugino T, et al. Enhanced poly(ADP-ribosyl)ation after focal ischemia in rat brain. J Cereb Blood Flow Metab,1998, 18(9): 991-997.
-
2Nanri K, Montecot C, Springhetti V, et al. The selective inhibitor of neuronal nitric oxide synthase, 7-nitroindazole, reduces the delayed neuronal damage due to forebrain ischemia in rats. Stroke, 1998, 29(6): 1248-1254.
-
3Nanri K, Takizawa S, Fujita H, et al. Modulation of extracellular glutamate concentration by nitric oxide synthase inhibitor in rat transient forebrain ischemia. Brain Res, 1996, 738(2): 243-248.
-
4Parmentier S, Bohme GA, Lerouet D, et al. Selective inhibition of inducible nitric oxide synthase prevents ischaemic brain injury. Br J Pharmacol, 1999, 127(2): 546-552.
-
5Wada K, Chatzipanteli K, Busto R, et al. Role of nitric oxide in traumatic brain injury in the rat. J Neurosurg, 1998, 89(5): 807-818.
-
6Gidday JM, Shah AR, Maceren RG, et al. Nitric oxide mediates cer ebral ischemic tolerance in a neonatal rat model of hypoxic preconditioning. J Cereb Blood Flow Metab, 1999, 19(3): 331-340.
-
7Zhang F, Iadecola C. Temporal characteristics of the protective effect of aminoguanidine on cerebral ischemic damage. Brain Res,1998, 802(1-2): 104-110.
-
8Fujimura M, Tominaga T, Kato I, et al. Attenuation of nitric oxide synthase induction in IRF-1-deficient glial cells. Brain Res, 1997,759(2): 247-250.
-
9Coert BA, Anderson RE, Meyer FB. A comparative study of the effects of two nitric oxide synthase inhibitors and two nitric oxide donors on temporary focal cerebral ischemia in the Wistar rat. J Neurosurg, 1999, 90(2): 332-338.
-
10Nagayama M, Zhang F, Iadecola C. Delayed treatment with aminoguanidine decreases focal cerebral ischemic damage and enhances neurologic recovery in rats. J Cereb Blood Flow Metab, 1998, 18(10): 1107-1113.
-
1许顺江,张建新.一氧化氮合酶抑制剂在脑缺血中的作用[J].河北医药,2000,22(12):940-941. 被引量:2
-
2王介明,梁建华,付瑞平,韩国杰.脑缺血过程的有关脑内病理机制[J].脑与神经疾病杂志,1998,6(5):320-321. 被引量:4
-
3张惠荣,杨红,陈志刚,宁建英.新生儿缺氧缺血性脑病与一氧化氮、一氧化氮合酶及血糖的关系探讨[J].中国误诊学杂志,2008,8(21):5135-5136.
-
4南彩,王高华,刘忠纯,王惠玲,王晓萍,肖玲.事件相关电位P300在抑郁症中的研究进展[J].国际精神病学杂志,2015,42(2):107-110. 被引量:7
-
5李合华,王玉梅,毛兴爱.辛伐他汀对蛛网膜下腔出血患者血清NO和NO S的影响[J].第四军医大学学报,2006,27(18):1719-1719.
-
6刘佰运.免疫系统与脑卒中[J].国外医学(脑血管疾病分册),1995,3(1):13-15. 被引量:12
-
7赵若华,孙洪涛,谢立群,张伟龙.脑血管病患者血清一氧化氮合酶水平变化的临床观察[J].武警医学,2001,12(11):652-653. 被引量:1
-
8苏海涛,刘建风,郑立志,柳爱军,王志军.丁苯酞软胶囊对蛛网膜下腔出血后血流动力学和血管痉挛的影响[J].中国临床研究,2015,28(5):621-623. 被引量:4
-
9刘燕,石尚金,彭凯润,鲍锦华,曾燕苗,温建新.高压氧综合治疗颅脑损伤合并动眼神经麻痹12例分析[J].中国临床康复,2002,6(16):2442-2442. 被引量:1
-
10赵颖,王苹,康立源.慢性脑缺血病理机制与实验研究进展[J].中国临床药理学杂志,2005,21(5):384-386. 被引量:9