经皮穿刺腰椎间盘切除术与透明质酸钠联合治疗腰椎间盘突出症

THE CLINICAL EFFECTS OF PERCUTANEOUS LUMBAR DISCECTOMY COMBINED WITH SODIUM HYALURONATE IN THE TREATMENT OF LUMBAR INTERVERTEBRAL DISC HERNIATION

目的 研究经皮穿刺腰椎间盘切除术 (PL D)与透明质酸钠联合治疗腰椎间盘突出症的疗效。方法 48例患者随机分为两组 ,采用经皮穿刺 PL D联合透明质酸钠骶管注射 (治疗组 ) 2 6例 ,单纯经皮穿刺 PL D(对照组 ) 2 2例。术后每 3个月随访一次 ,至术后 2年 ,根据改良的 Macnab标准判断疗效。结果 治疗组痊愈 16例 ,显效 5例 ,有效 4例 ,无效 1例。显效率为 80 .77%。对照组痊愈 8例 ,显效 7例 ,有效 5例 ,无效 2例。显效率为6 8.18%。两组疗效比较 ,有统计学意义 (P<0 .0 5 )。结论 腰椎间盘切除术与透明质酸钠联合治疗具有疗程短、见效快及安全等优点 。

Objective To investigate the therapeutic effect of percutaneous lumbar discectomy (PLD) combined with sodium hyaluronate (SH) injection in the treatment of lumbar intervertebral disc herniation. Methods Forty eight patients suffered from lumbar disc herniation were divided into two groups and treated by PLD combined with SH injection into epidural cavity (treatment group) or single PLD (control group) respectively. All patients were followed up for 24 months. The therapeutic effects in both groups were assessed and compared according to Macnab's criterion. Results The patients in the treatment group got much more significant improvement than those in the control group, with shorter therapeutic course and more safety. Conclusion PLD combined with SH injection into epidural cavity is more effective and safety in the treatment of lumbar disc herniation than of pure PLD.