T淋巴细胞核仁组成区相关蛋白检测在口腔颌面部肿瘤诊断中的意义

The significance of nucleolar organizer regions associated proteins of T lymphocytes in the diagnosis of oral and maxillofacial tumors.

目的 观察口腔颌面部肿瘤患者T淋巴细胞核仁组成区相关蛋白 (Ag -NORs)的表达特点 ,以探讨其在口腔颌面部肿瘤诊断中的价值。方法 采用肿瘤免疫图像分析系统及配套试剂对正常人、口腔颌面部良、恶性肿瘤患者外周血T淋巴细胞Ag -NORs进行检测和分析。结果 正常人组与口腔颌面部良、恶性肿瘤组Ag-NORs值差异均有显著性 (P <0 0 1) ;同时 ,良、恶性肿瘤组Ag -NORs值差异仍有显著性 (P <0 0 1)。结论 外周血T淋巴细胞Ag -NORs表达与口腔颌面部肿瘤呈良好的相关性 ;Ag

Objective To study the Ag-NORs expressive character of T lymphocyte in the patients with oral and maxillofacial tumors and to evaluate the value of diagnosis for the patients. Methods Nucleolar organizer regions (NORs) of T lymphocyte from normal adults, the patients with oral and maxillofacial benign tumors and the patients with oral and maxillofacial malignant tumors were analysed through KL imaging system. Results There were significant differences among normal adults, benign tumor, and malignant patients. Their average I S% values were 7 89±0 10, 6 13±0 16, and 4 96±0 12 respectively. Conclusion The expression of Ag-NORs of T lymphocyte has definite links with oral and maxillofacial tumors; the detection of Ag-NORs might play important role in the diagnosis of these tumors.