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基因多态性研究在原发性肾病综合征中的意义

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摘要 原发性肾病综合征(PNS)的病因尚不明确,近年来,随着分子生物学等研究手段的成熟和深入,一些研究结果显示某些基因如血管紧张素I转换酶基因、载脂蛋白E基因、血小板活化因子分解酶基因、人类白细胞抗原基因等的多态性与PNS的易感性、激素疗效、疾病复发、病理进展及预后明显相关。本文就近年来与PNS有关的基因多态性的研究进展作一综述。
作者 沈茜
出处 《国外医学(儿科学分册)》 2001年第6期281-283,共3页 Foreign Medical Sciences(Section of Pediatrics)
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