深圳市发热出疹性疾病血清流行病学分析

Seroepidemiological Analysis of Rash and Fever Illness in Shenzhen

为了解发热出疹性疾病 (RFIs)血清流行病学特征 ,对深圳市 1998～ 1999年发热出疹性病例同时检测麻疹、风疹IgM抗体 ,进行流行病学分析。共检测RFIs 32 8例 ,麻疹IgM抗体阳性率为 5 4 88%,风疹IgM抗体阳性率为 9 4 5 %。RFIs病例中麻疹和风疹发病高峰季节为春、夏季。麻疹发病以少年儿童为主 ,而风疹主要发病对象则出现两个非连续年龄高峰期 ,分别为儿童高峰期和青少年高峰期。 180例麻疹IgM抗体阳性病例中 ,免疫史不详和无免疫史占 83 89%。结果显示 ,RFIs病例中以麻疹、风疹为主 ,其分布也与麻疹、风疹流行特征相似。有必要将RFIs病例血清学监测列入计划免疫常规监测。

For understanding the seroepidemiological characteristics of rash and fever illness, we tested measles IgM(M-IgM)and rubella IgM(R-IgM)antibodies of RFIs cases in Shenzhen during the period of 1998~1999.328 RFIs cases were tested,the positive rate of M-IgM antibody was 54.88%,and that of R-IgM antibody was 9.45%.The seasonal peaks of measles and rubella of RFIs cases were very noticeable with incidence increasing at the end of spring and the beginning of summer.Most of the measles cases were 9 months ~9 years old,and the rubella cases were of the age groups of 1~3 and 10~29 years old.Of 180 M-IgM antibody positive cases,only 29 cases had vaccination history,151 cases were not vaccinated or not clear,accounting for 83.89%.Most IgM antibody positive cases of tested RFIs were measles and rubella, the distribution characteristics of RFIs was also similar to that of measles and rubella,so it is necessary to bring RFIs seroepidemiological surveillance into EPI routine surveillance