内镜超声引导下腹腔神经丛阻滞缓解进展期胰腺癌的疼痛

Endoscopic ultrasonography guided celiac plexus neurolysis for relieving abdominal pain in advanced pancreatic carcinoma

目的评价内镜超声引导下腹腔神经丛阻滞对胰腺癌患者的止痛作用。方法我们对16例进展期胰腺癌患者行内镜超声引导下的腹腔神经丛阻滞。在内镜超声的引导下,将细针穿刺至腹腔神经节的区域并注射无水乙醇。术后2d及每周用视觉类比量表(VAS)观察患者疼痛的程度。结果全部患者均成功进行了腹腔神经丛阻滞,并且没有1例发生严重并发症。一般术后头两天疼痛无明显缓解,术后一周疼痛明显缓解,并且疗效能持续较长时间。结论内镜引导下腹腔神经丛阻滞是治疗进展期胰腺癌疼痛较安全、有效的方法。

To evaluate the effect of endoscopic ultrasonography guided celiac plexus neurolysis (EUS CPN) on pain associated with pancreatic carcinoma. Methods EUS CPN was performed to relieve pain in 16 patients with advanced pancreatic carcinoma. By EUS, we used fine needle to puncture at the region of celiac ganglion and inject alcohol. The pain tensions were followed up under visual analogue scale rule at 2 days and weekly thereafter. Results All patients were performed EUS CPN successfully. No serious complications happened. No satisfactory pain control after the first 2 days of EUS CPN.Whereas it was relieved obviously after 7 days and the effects maintain a rather long term. Conclusion EUS CPN is a safe and effective method for releiving the pain in pancreatic carcinoma.