摘要
将羟基磷灰石 (HA)与DL 丙交酯 (DL LA)按一定比例混合 ,在辛酸亚锡引发下开环聚合得到HA微粒填充的聚DL 丙交酯 /羟基磷灰石 (PDLLA/HA)复合材料。在一定引发剂浓度下 ,HA的含量越大 ,粒径越小 ,PDLLA的分子量越低。扫描电子显微镜观察HA微粒均匀分布在PDLLA基质中 ,当PDLLA的分子量在 175 0 0 0～ 2 45 0 0 0范围内 ,HA含量 (HAwt %)为 30 %时 ,复合材料的弯曲强度达 90MPa ,剪切强度为 72MPa,模量为 6 .9GPa ,均高于其它体系。HA的引入不仅提高了材料的初始力学强度 ,而且还延缓了PDLLA的降解速度。
By mixing hydroxyapatite(HA) into DL-lactide monomer, prior to polymerization to poly(DL-lactide)(PDLLA), HA filled PDLLA composites were obtained. The more of the content and the smaller of the particles size of HA, the lower of the molecular weight of PDLLA, so less initiator must be added at higher HA content in order to obtain higher molecular weight PDLLA. Scanning electron microscope observations indicated that the HA particles in the PDLLA matrix were homogeneously dispersed. It was concluded that the PDLLA/HA composite had better bending strength and E-modulus when HAwt% was 30 than that of the other PDLLA/HA composites (HAwt%=15,50) and unfilled PDLLA (Mv=175000～245000). The degradation rates of PDLLA/HA composites were slowed down by incorporating HA particles.
出处
《中国生物医学工程学报》
CAS
CSCD
北大核心
2001年第6期485-488,515,共5页
Chinese Journal of Biomedical Engineering
基金
湖北省科技攻关资助项目
广东省自然科学基金资助项目
