核素三相骨显像在骨缺损移植修复中的价值

MULTIPHASE BONE IMAGING IN REPAIR OF BONE DEFECT

目的 :评价放射性核素三相骨显像在骨缺缺损移植修复过程中的价值。方法 :试验动物前肢分为骨形态形成蛋白 (BMP)和纤维蛋白粘和剂 (FS)复和物组 (A)、FS组 (B)和空白组 (C) ,于术后 1、2、4、8周分别行99mTc -MDP三相骨显像和组织学检查 ,并把所得结果进行比较。结果 :三相骨显像A组呈持续高灌注、高摄取 ,B、C组则在第 1、2周为高灌注 ,而后渐下降。各时间段摄取比组间比较AvsB、AvsCP <0 .0 0 1,BvsC术后2周P <0 .0 5 ,术后第 4、8周P >0 .0 5。组织学检查与骨显像结果吻合良好。结论

Objective:To evaluate the value of multiphase bone imaging in the transplantation and repair of bone defect.Methods:The experimental forearms of animals were divided into A(BMP/FS),B(FS) and C(Blank) groups.The 99m Tc-MDP multiphase bone imaging and histological tests were performed in the 1st,2nd,4th and 8th week after the operation,and the results were compared.Results:A group was higher perfused and absorbed more 99m TC-MDP than B and C group ( P <0.001).B group was higher perfused than C group ( P <0.05) in the 2nd week after the operation,and lower later.The results of histological testes were in conformity with bone imaging.Conclusions:The multiphase bone imaging was a good method of monitoring the repair of bone defect.