姜堰市食管癌危险因素的病例对照研究

A Contrast Study of the Risk Factors of Esophageal Cancer in Jiangyan City

目的 研究姜堰市食管癌的危险因素 ,为食管癌的预防监测提供依据。方法 1 999年 8月～ 2 0 0 0年 6月间采用问卷调查 ,对1 56例年龄范围在 32～ 80岁食管癌生存病例 ,按 1∶1配对 ,调查内容包括一般情况、居住环境、生活习惯、饮食嗜好、既往疾病及家族史等方面 1 1 0个问题。采用相对危险度的近似估计值比值比来估计各危险因素与食管癌的联系强度 ,用logistic回归模型做单因素和多因素分析 ,筛选出专业上有意义的食管癌危险因素。结果 与食管癌发病有关的变量 4个 ,分别为喜食烫食物、喜食酸辣食品、饮酒和吸烟。结论 喜食烫食物、喜食酸辣食品、饮酒和吸烟是具有统计学意义的食管癌危险因素。

Objective By study of the risk factors of esophageal cancer in Jiangyan City,evidences for further monitoring of the risk factors were provided..Methods A total of 156 cases (age range from 32～80 years old) of esophageal cancer survivors were surveyed by questionnaire, matched 1∶1 with controls, between August 1999 to June 2000. There were totally 110 questions in the questionnaire. The survey included general conditions, living environment, diet habit, living style, disease and family history, etc. Correlation power of all the risk factors and esophageal cancer were evaluated by the odd ratio(OR). Logistic regression model univalence and multivariate analysis were used to choose significant esophageal cancer risk factors on specialty. Results The 4 main variants like eating hot food, eating sour and hot food, drinking and smoking relate to the genesis of esophageal cancer. Conclusions Eating hot food, eating sour and hot food, drinking and smoking are statistically significant esophageal cancer risk factors.