十个民族转铁蛋白遗传多态性的研究

THE POLYMORPHISM OF TRANSFERRIN IN TEN CHINESE NATIONALITIES

应用超薄层聚丙烯(月先)胺凝胶等电聚焦方法,检测了我国十个民族共2562人的转铁蛋白遗传多态性。Tf~*C1基因频率依次为鄂温克族0.7571,鄂伦春族0.7467,维吾尔族0.7445,蒙古族0.7433,达斡尔族0.7417,西安汉族0.7205,满族0.7195,朝鲜族0.7136,藏族0.7096,回族0.7077,哈尔滨汉族0.7056。Tf~*C2基因频率顺序基本上与Tf~*C1相反。在蒙古族、西安汉族及满族中检出罕见变异型。

The transferrin(Tf) polymorphism of Ewenki, Mongolian, Oroqen, Tahur, Tibetan, Man-chu, Korean, Hui, Han(Xian, Harbin), Uighur nationalities living in China was investigated by means of ultra-thin polyacrylamide gel isoeletric focusing. The results showed that the Tf*C1 gene frequencies of eleven groups were higher than 0.7: Ewenki 0.7571, Oroqen 0.7467, Uighur 0.7445, Mongolian 0.7433, Tahur 0.7417, Han(Xian) 0.7205, Manchu 0.7195, Korean 0.7136, Tibetan 0.7096, Hui 0.7077, Han(Harbin) 0.7056, respectively. The Tf*C2 was the second major allele in these ethnical groups. The order of. Tf*C2 allele frequencies roughly was opposite to Tf*C1. In addition, some rare phenotypes were found, such as TfBDchi in Mongolian; TfDchiDchi in Han(Xian) and TfBC1 in Manchu.