醒脑静注射液对急性脑梗死意识障碍患者的影响

Influences of Xingnaojing injection(醒脑静注射液) on restoring consciousness in acute cerebral infarction

目的 :观察醒脑静注射液对急性脑梗死意识障碍的疗效。方法 :5 7例急性脑梗死意识障碍患者单盲随机分为 2组 ,对照组 2 8例在常规治疗基础上加用复方丹参注射液 16 m l加入生理盐水 2 5 0 ml静滴 ,每日 1次 ,14日为 1个疗程。治疗组 2 9例在常规治疗基础上加用醒脑静注射液 30 ml加生理盐水 2 5 0 ml静滴 ,每日 1次 ,14日为 1个疗程。采用格拉斯哥庇斯布赫昏迷分度表 (G Pcs)评定疗效。结果 :治疗组在治疗后各个时点上的 G Pcs平均分数均高于对照组 (P<0 .0 5或 P<0 .0 1)。结论 :醒脑静注射液对急性脑梗死意识障碍有催醒作用。

Objective:To observe the effects of Xingnaojing injection(醒脑静注射液) in the treatment of disturbance of consciousness in acute cerebral infarction.Methods:Fiftyseven patients were randomly divided into two groups.For routine medication,each of 28 patients in the control group were given compound saliva miltiorrhiza(复方丹参注射液) 16 ml in normal saline(NS) 250 ml,iv drip, and each of 29 patients in the treatment group were given Xingnaojing injection 30 ml(in NS 250 ml,iv drip,once a day),14 days as a therapeutic course in both groups.The degree of coma was evaluated by GlasgowPittsburgh coma scale (GPcs).Results:The increase in the average GPcs in the Xingnaojing injection treatment group in each time were higher than in the control group ( P <0 05 or P <0 01).Conclusions:Xingnaojing injection produces awakening effect in the disturbance of consciousness in acute cerebral infarction.