甲亢性及非甲亢性周期性瘫痪的临床和肌电图

The clinical and electromyographic analysis of thyrotoxic and nonthyrotoxic periodic paralysis

目的 探讨甲状腺功能亢进性周期性瘫痪 (TPP)与非TPP的临床及肌电图特点。方法 将 2 7例周期性瘫痪 (PP)病人分成TPP及非TPP两组 ,并比较两组病人的诱发因素、近端肌力、血钾以及肌电图。结果 TPP组发病无明确诱发因素较非TPP多 (P <0 .0 5 ) ;肌电图异常者在TPP较非TPP多 (P <0 .0 1) ;TPP和非TPP累及近端肌群及低血钾发生率相近 (P >0 .0 5 )。结论 肌电图在鉴别TPP和非TPP上有重要价值 ;PP病人应常规作肌电图及甲状腺功能检查 ,以确定是否有TPP存在。

Objective To investigate the clinical and electromyographic features of thyrotoxic periodic paralysis (TPP) and non TPP.Methods Twenty seven patients with periodic paralysis (PP) were divided into two groups, TPP and non TPP and evoking agents, proximal muscle strength, serum K + levels and electromyogram in two groups were compared.Results The number with no definite precipitating factors in the TPP group was significantly more than that in the non TPP one ( P < 0.05 );there were significantly more cases revealing abnormal electromyogram in the TPP group than that in the non TPP one ( P < 0.01 );and there were no significant difference between two groups about the incidence of involved proximal muscle and lowered serum K + levels.Conclusion Electromyogram plays an important role in differentiatng TPP and non TPP;the tests of electromyogram and thyroid function were supposed to perform routinely.