肠气通颗粒对动物胃肠功能的影响

Effects of Changqitong granules on function of animal gastrointestinal peristalsis

目的 :验证肠气通颗粒的主要功能。方法 :采用小鼠碳末推进法、小鼠胃酚红排空法、豚鼠离体回肠试验法。 结果:2 .12、1.0 6、0 .5 0 g/ kg肠气通颗粒均能促进正常小鼠胃排空运动 (P <0 .0 1) ;4.42、1.0 6、2 .12、0 .5 0g/ kg肠气通颗粒均可提高正常小鼠肠推进率 (P <0 .0 1～ 0 .0 5 ) ;0 .0 4,0 .0 2 g/ ml肠气通颗粒均能增强豚鼠离体回肠的收缩力 (P <0 .0 1)。 结论 :肠气通颗粒可促进肠蠕动。

Objective: To prove main action of Changqitong granules. Methods: It is adopted that experiment of carbon powder being put out into rat′s intestine, experiment of phenol red being eliminated into rat′s stomach and experiment to observe the contractibility of guinea-pig′s intestines. Results: Changqitong Granules (2.12, 1.06, 0.50 g·kg~ -1) could promote the movement of phenol red being eliminated in rat′s gastro-intestine (P<0.01); Changqitong Granules (4.42, 1.06 g·kg~ -1 and 2.12, 0.50 g·kg~ -1) could improve gastrointestinal peristalsis (P<0.01 and P<0.05); Changqitong Granules (0.04, 0.02 g·ml~ -1) could enhance the contraction of guinea pig′s intestines (P<0.01). Conclusion: Changqitong Granules can improve gastrointestinal peristalsis.