摘要
目的:考察头孢噻肟钠皮试液稳定性。方法:采用经典恒温加速试验法及留样观察法 ,考察头孢噻肟钠皮试液外观、p H值及紫外光谱的变化 ,用紫外分光光度法测定头孢噻肟钠的含量。 结果:恒温加速试验 2 5℃时预测其有效期为 3d;留样观察试验放置 1周 ,药品降解 9.8%。 结论:本品稳定性较差 ,室温避光保存不宜超过 3d。
Objective: To study the stability of cefotaxime sodium intracutaneous injection. Methods: The stability, appearance,pH and UV absorption spectrum was studied by accelerated testing and long-term testing. Results: There were no significant changes in pH and appearance. Cefotaxime sodium concentration droped to 90.2% at room temperature after one week. Conclusions: The stability of cefotaxime sodium intracutaneous injection is not good. Under the storage conditions of room temperature and avoiding sunlight, the favourable storage life should not be more than 3 days.
出处
《新疆医科大学学报》
CAS
2001年第4期359-360,共2页
Journal of Xinjiang Medical University