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葛根素对降低2型糖尿病患者微量白蛋白尿的临床观察 被引量:1

Clinical Observations of Kakonein on Lowering Microalbuminuria in Treating Type Ⅱ Diabetes Cases
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摘要 目的 :观察葛根素对 2型糖尿病早期肾脏病变的疗效。方法 :对 73例 2型糖尿病 2 4 h尿微量白蛋白 (UAE)在 30~ 30 0 mg/ 2 4 h者随机分成两组 ,治疗组 37例 ,每天静滴葛根素 5 0 0 mg,共 2周 ;对照组用生理盐水静滴 ,共 2周。观察血糖及尿 UAE变化。结果 :两组治疗前后比较差异有显著性意义 ,P<0 .0 1。结论 :葛根素对 2型糖尿病早期肾脏病变疗效明显 。 Objective:To observe the therapeutic efficacy of kakonein in treating early renal damage in type Ⅱ diabetes cases.Methods:73 cases whose VAE was between 30 to 300 mg/24 hours were divided at random into two groups:Kakanein group(37 cases treated with kakonein 500 mg daily intravenously for 2 weeks) and control treated with NS.Results:The serum glucose level and urine VAE existed significance between the 2 groups( P <0.01).Conclusions:Kakonein was effecitive in treating early renal damage of type Ⅱ diabetes cases.
出处 《浙江中西医结合杂志》 2001年第12期742-743,共2页 Zhejiang Journal of Integrated Traditional Chinese and Western Medicine
关键词 2型糖尿病 肾脏病变 尿微量白蛋白 葛根素 Type Ⅱ diabetes Renal damage Kankonein microalbuminuria Therapeutic evaluation
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参考文献3

  • 1[1]Hostetter TH.Pathogenesis of diabetic glomerulopathy :hemodynamic considerations.Semin Nephrol,1990,10:219~227.
  • 2[2]Cohet MP.Nonenzymatic glycation and enhanced polyols pathway activity in the pathogenesis of diabetic nephropathy.Contrib Nephrol,1989,73:59~70.
  • 3[3]Tomuras S,Schrier RW,Keauc WF,et al.Coagulationa and fibrinolysis in pstients with chronic renal faiture undergoing conservative treatment.Thromb Res,1991,64 :81~91.

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