孕妇自控镇痛对产程的影响

Effects of patient controlled epidural analgesia on labor process.

目的 探讨孕妇自控硬膜外镇痛 (PCEA)对产程的影响。方法 3 5例使用PCEA(A组 ) ,4 0例为对照组 (B组 ) ;测定两组母血、脐血和羊水中前列腺素E2 (PGE2 )浓度 ;观察产痛程度、产程进展。结果 用药后两组产痛评分比较有显著差异 (P <0 0 5 ) ;两组内、组间母血、脐血和羊水中PGE2 、活跃期与第三产程时间及剖宫产率的比较均无显著差异 (P >0 0 5 ) ;两组第二产程时间、阴道手术助产率比较有显著差异 (P <0 0 5 )。结论 PCEA镇痛效果好 ,对母儿均无明显影响 ,值得在临床推广。

Objective To investigate the effects of patients controlled epidural analgesia(PCEA)on labor process.Methods 35 women were selected for the study group,40 as control.We measured the concentrations of prostaglandin E 2 in maternal serum,in umbilical cord serum and amniotic fluid.The labor pain and progress of labor were compared.Results The score of labor pain showed significant difference between the 2 groups(P<0.05).There was no difference compared with each stage of labor process about the concentrations of prostaglandin E 2 in maternal serum in each group and also in the concentrations of prostaglandin E 2 in maternal serum,umbilical cord serum and amniotic fluid(P>0.05).There was no difference between two groups in the first stage,the third stage and rate of cesarean section(P>0.05).The second stage vaginal instrumental delivery were significantly different between the two groups(P<0.05).Conclusion PCEA has a good analgesia effect,no obvious influence on mother and fetus.It is valuable to use PECA widely in our clinical work.