平阳霉素碘油乳剂子宫动脉灌注治疗症状性子宫肌瘤22例临床分析

Clinical analysis of uterine arteries perfusion with Pingyangmycin Lipiodol emulsion in the management of symptomatic leiomyomas in 22 cases.

目的 评价平阳霉素碘油乳剂 (PLE)子宫动脉灌注治疗症状性子宫肌瘤的效果及副反应。方法 对2 2例症状性子宫肌瘤患者用PLE行子宫动脉灌注 ,观察术后症状缓解情况、子宫缩小程度和副反应的发生。结果 2 0例完成灌注治疗患者 ,临床症状显著改善 ;16例得到影像学随访者 ,子宫体积平均缩小 5 0 5 %;主要副反应为下腹疼痛 ,严重者与误栓有关。结论 PLE子宫动脉灌注是一种以保留子宫为特征的治疗症状性子宫肌瘤的有效方法。

Objective To evaluate the effectiveness and side effects of uterine arterial perfusion with Pingyangmycin Lipiodol emulsion(PLE) in the management of symptomatic leiomyomas.Methods Uterine arterial perfusion with PLE was performed in 22 patients with symptomatic leiomyomas.The relief of symptoms,uterine size changes and side effects were observed after the procedure.Results Twenty(90^9%)of the 22 patients had technically successful procedures.The clinical symptoms were obviously improved;16 patients who had received the imaging examinations showed a mean reduction of 50^5% in uterine volume.The main side effects were the pain in the lower abdomen,which in severe cases was the result of embolization in improper arteries.Conclusion The uterine arterial perfusion with PLE is an effective therapy in the management of symptomatic leiomyomas and the therapy is characterized by retaining patients' uterus.