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盐酸安非他酮缓释片的研究

Preparation of Bupropion Hydrochloride Sustained - release Tablets
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摘要 目的:制备盐酸安非他酮缓释制剂。方法:采用正交设计优化了盐酸安非他酮的缓释片处方并测定其释放度。结果:本品在不同介质中均有明显的缓释效果,可持续释放10h以上。结论:本文采用的处方具有工艺简单、成本低廉的优点。 Objective : To prepare the bupropion hydrochloride sustained release tablets, Method:Orthogonal design was adopted far optimizing the formulation of bupropion hydrochloride extended release tablets and its release test was measured. Results: This product has obviously extended realease effect in different medium and can release over 10 h . Conclusion:The formulation of this preparation ia simple and cheap.
作者 郑意端 王鹏
出处 《中国医药导刊》 2001年第5期390-391,共2页 Chinese Journal of Medicinal Guide
关键词 盐酸安非他酮 抗抑郁剂 缓释片 制备工艺 bupropion hydrochloride sustained - release tablets
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  • 1J. W. A. Findlay,J. Wyck Fleet,P. G. Smith,R. F. Butz,M. L. Hinton,M. R. Blum,D. H. Schroeder. Pharmacokinetics of bupropion, a novel antidepressant agent, following oral administration to healthy subjects[J] 1981,European Journal of Clinical Pharmacology(2):127~135

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