含苦参中药复方消毒液杀菌效果的试验观察

EXPERIMENTAL OBSERVATION ON GERMICIDAL EFFICACY OF COMPOUND CHINESE DRUG DISINFECTANT CONTAINING RADIX SOPHORAE FLAVESCENTIS

将中药苦参、蛇床子、大黄等水煎提取液加芳香油制成淡黄色的消毒液（ｐＨ ５．５～６．０）。采用载体定量杀菌试验，观察其杀灭微生物效果。结果，以该中药复方消毒液加蒸馏水的５倍稀释液，对布片上金黄色葡萄球菌和大肠杆菌分别作用３ ｍｉｎ与４ ｍｉｎ，以其原液对布片上白色念珠菌作用 ２ ｍｉｎ，杀灭率均≥９９．９０％。染布片的菌悬液中含体积分数为５０％的小牛血清时，对其杀菌效果有轻度影响。为此，使用中应注意防止有机物对其杀菌作用的影响。

Light yellow-colored disinfectant solution (pH 5.5~6.0) was prepared from water decoction of Chinese drugs such as Radix Sophorae Flavescentis, Fructus Cnidii and Radix Rhei with addition of perfume oil. Carrier quantitative germicidal test was used to observe its germicidal efficacy. The results showed that 5 - fold dilute solution of this compound Chinese drug disinfectant prepared by adding distilled water with a 3 minute and 4 minute contact time killed ≥ 99.90% of Staphylococcus aureus and Escherichia coli on cloth strips respectively. Its stock solution with a 2 minute contact time killed ≥99.90% of Candida albicans on cloth strip. When the bacterial (fungal) suspension contaminating the cloth strips contained 50% by volume of calf serum, its germicidal efficacy was slightly influenced. There- fore, attention should be paid to prevent the influence of organic substances on its germicidal efficacy during use.