同时快速检测全血cTnI、MB、CK-MB诊断急性心肌梗死的评估

目的 评估同时快速检测全血肌钙蛋白、肌红蛋白、肌酸激酶同工酶的金标定性法在急性心肌梗死 (AMI)早期诊断中的价值。方法 应用美国PBM公司试剂盒测定 59例AMI发病后不同时间和 43例不稳定性心绞痛患者全血中cTnI、MB、CK MB并与生化法测定CK、CK -MB作对照。结果 59例AMI在症状出现后 ,(3.9± 2 .3)h首次检测 ,金标定性法阳性率cTnI>6 0 % ,CK -MB >6 2 % ,MB >6 5%。酶法检测CK -MB、CK升高 (与新法比较 )分别为 45% (P <0 .0 1 )和 36 % (P <0 .0 0 1 ) ;此后 4h再次检测 ,上述结果分别为 98%、94%、92 %、91 % (P >0 .0 1 )和 6 1 % (P <0 .0 0 1 )。在AMI发病 1周后 ,定性法cTnI阳性率仍达 76 .4%。结论 同时快速检测cTnI、MB、CK

Objective\ To study the significance simultaneous rapid measurement of whole blood myoglobin ?creative kinase MB and cardiac troponin I in Acute Myocardial Infarction. Methods PBM of USA reagent-box was used to analysed the indoxes in 59 cases of a Acute myocardial infarction coming on in differ time, compared with those in 43 cases of astatic anginaPectoric. Results 59 Positive rate were troponin I>60%, creative kinase MB>62%, myoglobin65% cases AMI come on first time?Conclusion Simultaneous rapid measurement of whole blood myoglobin ?creative kinase MB and cardiac troponin I are a better predicting index forAMI.