早孕妇女解脲支原体感染引起自然流产的临床观察

Clinical Observation Of Spontaneous Abortion Caused By Infection Of Ureaplasms Urealyticum In Early-pregnant Women

目的:探索解脲支原体(UU)感染与自然流产的关系。方法:将标本置入 UU液培养基中,37 C培养 6小时后观察液体颜色变化。对53例早孕自然流产妇女(观察组)和51例早孕人工流产妇女(对照组)取宫颈分泌物进行UU检测。结果:观察组与对照组UU阳性率分别为47.2％、25.5％,两组比较差异显著(P<0.05),观察组自然流产的次数与UU培养阳性率呈正相关,观察组宫内刮出组织病理检查,UUC阳性与UUC阴性比较,差异显著(P<0.01),经治疗后UU阳性转阴性者31例,转阴率为86％。结论:宫颈UU感染与自然流产密切相关,是引起自然流产主要病因之一。

Objectiv:To examine whether the infection of Ureplasms Urealyticum(UU)is correlated with spontaneous abortion. Methods: We detected the UU occurence in cervical secretion of 53 early-pregnant spontaneous aborive women and 51 early-pregnant induced abortive women as control. We put the cervical secretion into UU culture medi-ums for inoculation,then put them in 37 C warm box to culture. 6 hours later,the liquid color changes were observed. Results:The UU positive frequency in spontaneous abortive group(47.2%) was significantly higher than that in in-duced abortive group(25.5%)( P≤0.05).The times of spontaneous abortion were positive relative to positive fre-quency of Ureaplasms Urealyticum culture (UUC). The results of pathological examination of intrauterine tissues were significantly different between the spontaneous abortive women of UUC positive and women of UUC negative(P<0.01). After treatment,31 women of UUC positive(86%) became UUC negative. Conclusion:Cervical UU infection is correlated with spontaneous abortion,and it may be one of the important factors responsible for spontaneous abor-tion.