24例脉络膜黑色素瘤临床病理分析

Clinico-Pathological Analysis of Choroidal Melanoma:A Report of 24Cases

目的:总结经病理证实的24例脉络膜黑色素瘤。方法:分析其临床、B超、CT特点及病理改变。结果:24例中,男15例,女9例年龄10～61岁,平均年龄41.66岁。病程1周～1.5年。视力主要症状为视野缺损,视力下降,眼底可见棕褐色实性隆起。病理:梭型细胞型11例,上皮样细胞型7例,混合细胞型5例,1例未分型。结论:视力与病程及肿瘤所占位置有关,预后与肿瘤细胞分型及肿瘤治疗早晚有关,并指出早期准确诊断是治疗的关键。

Objective:To summarize the clinical experience of24cases of choroidal melanoma proved pathologically.Methods:The clinical manifestations,features of B-ultrasonog-raphy,computed tomography and pathological changes of these patients were analysied.Results:Among the24patients,15were male and9female.The age ranged from10to61years with a mean age of41.66and the course of disease lasted from1week to1.5years.Visual acuity:No light sensation4.9.The chief symptoms and signs were impaired visual field,diminished visual acuity and brown bulging out of fundus.Pathology:Spindle cell type11,epithelioid cell type7,mixed cell type5and unidentified type1.Conclusion:The visual acuity is associated with the course of disease,and site of tumor,and the prognosis is related to the tumor cell types and the patient to be treated earlier or later.Early accurate diagnosis is the key to treatment.